Microbial oxygenation of cycloheptyl-N-phenylcarbamate and (±)-trans-2-fluorocycloheptyl-N-phenylcarbamate with Beauveria bassiana

Article abstract of DOI:10.1016/S0040-4020(97)10147-8

The title biotransformation of 1 gave trans-4-hydroxycyclohept-1-yl-carbamate (3, 10%, 62% ee), its consecutive ketone 5 (12%) and the racemic cis-isomer 4 (1.8%). Similarly, the racemic trans-2-fluoro analogue 2 yielded mainly four optically active alcoh