Adrenoceptor blocking agents. 2. 2-(alpha-Hydroxyarylmethyl)-3,3-dimethylaziridines, a new class of selective beta2-adrenoceptor antagonists.

DOI: 10.1021/jm00199a012

Source and publish data:

Journal of medicinal chemistry p. 68 - 72 (1978)

Update date:2022-07-29

Topics:

Authors:

Jain Jain

Khandelwal

Tripathi

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Article abstract of DOI:10.1021/jm00199a012

Threo- and erythro-2-(alpha-hydroxybenzyl)-3,3-dimethylaziridines (1a and 1b) and threo-2-[alpha-hydroxy(2-naphthyl)methyl]- and 2-[alpha-hydroxy(3,4-dichlorobenzyl)]-3,3-dimethylaziridines (1d and 1c) have been prepared as conformationally restricted ana

Full text of DOI:10.1021/jm00199a012

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