Tetrahedron Asymmetry p. 3353 - 3358 (2003)
Update date:2022-07-29
Topics:
Galeazzi, Roberta
Martelli, Gianluca
Mobbili, Giovanna
Orena, Mario
Rinaldi, Samuele
The 4-benzyloxymethyl pyrrolidin-2-one, 5, was alkylated leading to 3,4-trans-disubstituted pyrrolidin-2-one 6 in good yield and total diastereoselection, as shown by 1H NMR data and NOE experiments. After reduction of the carbonyl group to giv
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