Lipids p. 666 - 668 (1977)
Update date:2022-07-30
Topics:
Hays
Parks
Pierce Jr
Oehlschlager
15-Aza-24-methylene-D-homocholesta-8,14-dien-3β-ol, an antimycotic agent, at a concentration of 75 ng/ml inhibited ergosterol biosynthesis in S. cerevisiae strain 3701B resulting in the accumulation of an unusual sterol. Experimental data presented indicate that this sterol is ergosta-8,14-dien-3β-ol. The accumulation of the compound is supportive of current models of biosynthetic pathways for sterols in yeast and is consistent with inhibition by the azasterol of the Δ14 sterol reductase.
Baoding City Light Industry And Textiles Imp.& Exp. Corp. Chemical Department.
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Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd
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Tangshan Moneide Trading Co., Ltd.
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Doi:10.1021/ja1028556
(2010)Doi:10.1016/j.tet.2003.09.099
(2003)Doi:10.1016/j.tet.2003.09.100
(2003)Doi:10.1016/j.tet.2003.09.084
(2003)Doi:10.1021/ja00457a032
(1977)Doi:10.1021/ja00462a041
(1977)
