Antischistosomal effects of 5-(2,4,5-trichlorophenyl)hydantoin and related compounds

DOI: 10.1021/jm00222a006

Source and publish data:

Journal of Medicinal Chemistry p. 1569 - 1572 (1977)

Update date:2022-08-03

Topics:

Authors:

Werbel Werbel

Elslager

Islip Islip

Closier Closier

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Article abstract of DOI:10.1021/jm00222a006

5-(2,4,5-Trichlorophenyl)hydantoin and several analogues effected an 80-90% reduction of live schistosomes in infected mice at doses ranging from 265 to 329 mg/kg per day when administered orally in the diet for 14 days. The sodium salt of 5-(2,4,5-trichl

Full text of DOI:10.1021/jm00222a006

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