Antimitotic agents. Chiral isomers of ethyl [5-amino-1,2-dihydro-3-(4- hydroxyphenyl)-2-methylpyrido[3,4-b]pyrazin-7-yl]carbamate

DOI: 10.1021/jm00084a003

Source and publish data:

Journal of Medicinal Chemistry p. 988 - 993 (1992)

Update date:2022-07-30

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Authors:

Temple Jr.

Rener Rener

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Article abstract of DOI:10.1021/jm00084a003

Metabolism studies with ethyl [5-amino-1,2-dihydro-2-methyl-3- phenylpyrido[3,4-b]pyrazin-7-yl]carbamate (1) in mice were reported previously to give a hydroxylated metabolite, which was methylated to give a methoxy derivative. The metabolite and its deri

Full text of DOI:10.1021/jm00084a003

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Product name:Carbamic acid, [6-amino-4-[[2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]-5-nitro -2-pyridinyl]-, ethyl ester

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