Antimitotic agents. Chiral isomers of ethyl [5-amino-1,2-dihydro-3-(4- hydroxyphenyl)-2-methylpyrido[3,4-b]pyrazin-7-yl]carbamate

DOI: 10.1021/jm00084a003

Source and publish data:

Journal of Medicinal Chemistry p. 988 - 993 (1992)

Update date:2022-07-30

Topics:

Authors:

Temple Jr.

Rener Rener

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00084a003

Metabolism studies with ethyl [5-amino-1,2-dihydro-2-methyl-3- phenylpyrido[3,4-b]pyrazin-7-yl]carbamate (1) in mice were reported previously to give a hydroxylated metabolite, which was methylated to give a methoxy derivative. The metabolite and its deri

Full text of DOI:10.1021/jm00084a003

Products guided by the article

Product name:Carbamic acid, [6-amino-4-[[2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]-5-nitro -2-pyridinyl]-, ethyl ester

Cas No:646073-52-1

R&D Labs maybe for 646073-52-1

Shanghai Send Pharmaceutical Technology Co., Ltd.

website:http://www.shsendpharma.com

Contact:021-58088081, +8613585868794

Address::Room A601, Building 1,NO. 800 Qingdai Road Pudong District Shanghai,China
Pengchen New Material Technology Co., Ltd.

Contact:+86-512-63680537

Address:99.6 km of national road 318, Meiyan Community,Pingwang Town, Wujiang District, Suzhou 215225
Jitat Company Ltd

Contact:852-27701081

Address:Room 2509, New Tech Plaza, 34 Tai Yau St., San Po Kong, HK
Wuxi Morality Chemical Co., Ltd(expird)

Contact:

Address:B/7F, 321th WuYun Rd, Wanda Plaza, Wuxi City, 214174, China
PharmaResources(Kaiyuan)CO,.Ltd

Contact:+86-21-50720028

Address:No.3, Beihuan Road, Economic Development District, Kaiyuan City, Tieling City, Liaoning Province, China 112300

Relevant to this article

Synthesis of erythro-α-Amino β-hydroxy Carboxylic Acid Esters by Diastereoselective Photocycloaddition of 5-Methoxyoxazoles with Aldehydes

Doi:10.1021/jo034830h
(2003)
Doi:10.1016/S0022-1139(00)82143-0
(1977)
An efficient solvent-free synthesis of NH-pyrazoles from β-dimethylaminovinylketones and hydrazine on grinding

Doi:10.1016/j.tetlet.2010.04.038
(2010)
Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives: High-affinity ligands to the α₂δ subunit of voltage gated calcium channels

Doi:10.1016/j.bmcl.2003.12.036
(2004)
Homoleptic tetrahydrometalate anions MH₄^-(M = Sc, Y, La). Matrix infrared spectra and DFT calculations

Doi:10.1021/ja020112l
(2002)
Total synthesis of ribostamycin

Doi:10.1016/S0040-4039(00)77906-8
(1976)

Article Doi