Reduction of β-Hydroxy Ketones with Catecholborane. A Stereoselective Approach to the Synthesis of Syn 1,3-Diols

DOI: 10.1021/jo00305a005

Source and publish data:

Journal of Organic Chemistry p. 5190 - 5192 (1990)

Update date:2022-08-05

Topics:

Authors:

Evans, David A.

Hoveyda, Amir H.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00305a005

The stereoselective reduction of acyclic β-hydroxy ketones to syn 1,3-diols may be achieved with the mild reducing agent catecholborane.In certain instances reaction stereoselectivity may be enhanced through rhodium(I) catalysis.

Full text of DOI:10.1021/jo00305a005

Products guided by the article

Product name:(3R^*,5S^*)-2,6-dimethyl-3,5-heptanediol

Cas No:65534-62-5

R&D Labs maybe for 65534-62-5

Taizhou Shengxing Chempharm Co.,Ltd

Contact:+86-576-88516600

Address:Yantou Chemical Zone Jiaojiang Taizhou Zhejiang China
Antaeus Bio-technology Co., LTD(expird)

Contact:021-31252569

Address:shanghai pudong
Tractus Company Limited

Contact:+852-8198 2399

Address:9E, Leapont Industrial Building, 18-28 Wo Liu Hang Road, Shatin, New Territories, Hong Kong
waho int'l company

Contact:+86-579-85206992

Address:No 451 chouzhou north road ,room 1106 int'l business center , yiwu ,china
Suzhou Wedo Chemicals Co., Ltd.

Contact:86 512 58100425

Address:Zonger Road, DongSha Industry Park , Zhangjiagang, Jiangsu, China

Relevant to this article

Doi:10.1002/hlca.19470300655
(1947)
Conjugated and Cross-Conjugated ?-Extended Cycloproparanes with dithiole and Cyclopentadiene Functionality

Doi:10.1002/ejoc.200300619
(2004)
Reactions of Iron Atoms with Benzene and Cyclohexadienes in Argon Matrices: Iron-Benzene Complexes and Photolytic Dehydrogenation of Cyclohexadiene

Doi:10.1021/ja00281a028
(1986)
2,4,6-trialkylphenyl-2H-phospholes from slightly aromatic 1H-phospholes and their use in [4 + 2] cycloaddition reactions

Doi:10.1002/hc.10151
(2003)
Synthesis of 2-Aryl-2 H-benzotrizoles from azobenzenes and N-sulfonyl azides through sequential rhodium-catalyzed amidation and oxidation in one pot

Doi:10.1021/ol501250t
(2014)
FLUOROCARBON DERIVATIVES OF NITROGEN. PART 10. PREPARATION OF HEPTAFLUORO- AND 1-CHLOROHEXAFLUORO-2-NITROSOPROPANE, AND CONVERSION OF THE LATTER TO CHLOROPENTAFLUOROACETONE OXIME

Doi:10.1016/S0022-1139(00)85122-2
(1984)

Article Doi