Reduction of β-Hydroxy Ketones with Catecholborane. A Stereoselective Approach to the Synthesis of Syn 1,3-Diols

DOI: 10.1021/jo00305a005

Source and publish data:

Journal of Organic Chemistry p. 5190 - 5192 (1990)

Update date:2022-08-05

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Authors:

Evans, David A.

Hoveyda, Amir H.

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Article abstract of DOI:10.1021/jo00305a005

The stereoselective reduction of acyclic β-hydroxy ketones to syn 1,3-diols may be achieved with the mild reducing agent catecholborane.In certain instances reaction stereoselectivity may be enhanced through rhodium(I) catalysis.

Full text of DOI:10.1021/jo00305a005

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