ENZYME-CATALYZED SYNTHESIS OF (S)-CYANOHYDRINS AND SUBSEQUENT HYDROLYSIS TO (S)-α-HYDROXY-CARBOXYLIC ACIDS

DOI: 10.1016/S0040-4039(00)88777-8

Source and publish data:

Tetrahedron Letters p. 1249 - 1252 (1990)

Update date:2022-08-04

Topics:

Authors:

Effenberger, Franz

Hoersch, Brigitte

Foerster, Siegfried

Ziegler, Thomas

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)88777-8

(S)-Cyanohydrins 2 are obtained with high enantioselectivity from aromatic aldehydes and HCN in the presence of (S)-oxynitrilase (E.C.4.1.2.11).Acid-catalyzed hydrolysis of the cyanohydrins 2 affords the corresponding (S)-α-hydroxy carboxylic acids 3 without racemization.

Full text of DOI:10.1016/S0040-4039(00)88777-8

Products guided by the article

Product name:Benzeneacetic acid, a-hydroxy-3-phenoxy-, (S)-

Cas No:65635-38-3

R&D Labs maybe for 65635-38-3

TC CHEMICALS CO.,LTD

Contact:0550-7041128 0550-7090578

Address:Wangdian Street,Xinjie Town
ANHUI WEICHI CHEMICAL CO.,LTD

website:http://www.weichichem.com

Contact:+8613912949432

Address:Fine Chemical Industrial Base,Wujiang town,He County,Anhui China.
Valiant Fine Chemicals Co., Ltd.

Contact:+86 535 6101878/6374484

Address:11 Wuzhishan Rd.,YTETDZ,Yantai,264006,Shandong,China
Ningbo Hi-tech Zone Nice-Synth Chemical Industry Ltd.

Contact:+86-(574)-81110986

Address:No. 1210, Building 3, Wante Business Centre, Hi-tech Zone, Ningbo
Wuxi D-Stone International Co., Ltd.

Contact:+86-510-82740567

Address:21F Hengtong Int'l Centre, 215Zhongshan Road, Wuxi, Jiangsu,China

Relevant to this article

Synthesis and Molecular Recognition of Pyrenophanes with Polycationic or Amphiphilic Functionalities: Artificial Plate-Shaped Cavitant Incorporating Arenes and Nucleotides in Water

Doi:10.1021/jo035188u
(2004)
Enantioselective Access to 2,7-Cis-Disubstituted Oxepanes: Formal Synthesis of (+)-Isolaurepan

Doi:10.1021/ol036299i
(2004)
γ-Functionalization of α,β-Unsaturated Nitrile in Mild Condition: Versatile Synthesis of 4-Aryl-2-Bromopyridines

Doi:10.1002/adsc.201901002
(2019)
Stereochemistry of Nucleophilic Addition Reactions. 10. Preparation of 2-C-Diacetylmethyl and 2-C-Acetylmethyl Derivatives with the Altro, Gluco, and Manno Configuration from Methyl 4,6-O-Benzylidene-2,3-dideoxy-3-nitro-α-D-erythro-hex-2-enopyranoside

Doi:10.1246/bcsj.53.2322
(1980)
Peterson Olefination of (α-Methoxybenzyl)silane with Aldehydes and Ketones Leading to Vinyl Ethers

Doi:10.1246/bcsj.58.3385
(1985)
Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery

Doi:10.1038/s41557-020-0530-4
(2020)

Article Doi