Novel modified tripeptide inhibitors of α4β7 mediated lymphoid cell adhesion to MAdCAM-1

DOI: 10.1016/S0960-894X(98)00286-8

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1601 - 1606 (1998)

Update date:2022-07-31

Topics:

Authors:

Shroff Shroff

Schwender

Baxter Baxter

Brookfield

Payne Payne

Cochran Cochran

Gallant Gallant

Briskin Briskin

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00286-8

MAdCAM-1 specifically binds the lymphocyte integrin α₄β₇ and participates in the homing of leukocytes to intestinal mucosal sites. The LDT sequence located on the CD loop of MAdCAM-1 is an important binding site for MAdCAM-1/α_4<

Full text of DOI:10.1016/S0960-894X(98)00286-8

Products guided by the article

Product name:L-Threonine, O-(1,1-dimethylethyl)-N-[(phenylmethoxy)carbonyl]-, 2-(trimethylsilyl)ethyl ester

Cas No:65903-67-5

R&D Labs maybe for 65903-67-5

Jiangsu Fengshan Group Co., Ltd.

Contact:86-25-86558671

Address:1903,Central International Mansion 105-6 North Zhongshan Road, Nanjing, China
Compro Shijiazhuang Fine Chemical Co., Ltd

Contact:0086-311-89689838

Address:Economic and Technological Development Zone of Shijiazhuang,Hebei
Heliosense Biotechnologies, Inc.

Contact:+86-592-5667290

Address:Xiamen Torch Hi-tech Zone Venture Weiye Building S506
Aminodiscovery Co.,Ltd.

Contact:+86-535-8888888

Address:No.161 Haishi Rd.
Zhejiang Genebest Pharmaceutical Co.,Ltd.

Contact:0086-571-63532866

Address:No.1 Jinboshi Rd Lishan Town Fuyang City Zhejiang Province China

Relevant to this article

New Approach to Phosphinoalkynes Based on Pd- and Ni-Catalyzed Cross-Coupling of Terminal Alkynes with Chlorophosphanes

Doi:10.1021/ol035562c
(2003)
Doi:10.1055/s-1978-24691
(1978)
Regioselective and Stereospecific Azidation of 1,2- and 1,3-Diols by Azidotrimethylsilane via a Mitsunobu Reaction

Doi:10.1021/jo9906375
(1999)
Doi:10.1246/bcsj.51.225
(1978)
Doi:10.1246/bcsj.51.563
(1978)
Conversion of Coordinated Carbon Monoxide into Carbon Dioxide via Oxygen-atom transfer from Coordinated Nitrite: Thermolysis of Ru(NO2)2(CO)2(PPh3)2

Doi:10.1021/ja00402a024
(1981)

Article Doi