A SIMPLE PREPARATION OF 2-(ACYLAMINO)-2-DEOXY-3,4:5,6-DI-O-ISOPROPYLIDENE-aldehydo-D-GLUCOSE DIMETHYL AND DIBENZYL ACETAL

Article abstract of DOI:10.1016/S0008-6215(00)83838-0

When treated with a large excess of 2,2-dimethoxypropane or 2,2-dibenzyloxypropane in 1,4-dioxane solution in the presence of p-toluenesulfonic acid, 2-acetamido-2-deoxy-D-glucose and 2-(benzyloxycarbonylamino)-2-deoxy-D-glucose yield the corresponding 3,4:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl or dibenzyl acetal in good yield.