Intramolecular Kinetic Deuterium Isotope Effects on Microsomal Hydroxylation and Chemical Chlorination of Toluene-α-d1 and Toluene-α,α-d2

DOI: 10.1021/ja00310a066

Source and publish data:

Journal of the American Chemical Society p. 7164 - 7167 (1985)

Update date:2022-08-02

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Authors:

Hanzlik, Robert P.

Hogberg, Kerstin

Moon, Joseph B.

Judson, Charles M.

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Article abstract of DOI:10.1021/ja00310a066

Deuterated toluenes PhCH2D and PhCHD2 were synthesized and subjected separately to microsomal hydroxylation in vitro.Mass spectral analysis of the resulting benzyl alcohols indicated substatial excess retention of deuterium, a consequence of the combined

Full text of DOI:10.1021/ja00310a066

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