Nucleosides and Nucleotides. Part 25. Synthesys of a Protected 1-(2'-Deoxy-β-D-ribofuranosyl)-1H-benzimidazole 3'-Phosphate

DOI: 10.1002/hlca.19870700117

Source and publish data:

Helvetica Chimica Acta p. 138 - 141 (1987)

Update date:2022-08-04

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Authors:

Papageorgiou, Christos

Tamm, Christoph

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Article abstract of DOI:10.1002/hlca.19870700117

1-(2'-Deoxy-5'-O-dimethoxytrityl-β-D-ribofuranosyl)-1H-benzimidazole 3'-<(p-chlorophenyl) (2-cyanoethyl)phosphate> (6) has been synthesized from 1-(β-D-ribofuranosyl)-1H-benzimidazole (3b) using regiospecific 2'-deoxygenation.The latter compound was obtained by glycosylation of benzimidazole with the D-ribose derivative 2 leading exclusively of the β-D-anomer.

Full text of DOI:10.1002/hlca.19870700117

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