Tetrahedron p. 393 - 412 (1992)
Update date:2022-07-30
Topics:
Niwa, Haruki
Miyachi, Yasuyoshi
Okamoto, Osamu
Uosaki, Youichi
Kuroda, Akio
et al.
A total synthesis of the natural enantiomer of integerrimine (1), a twelve-membered dilactonic pyrrolizidine alkaloid of retronecine type has been achieved through the enantioselective synthesis and regioselective coupling of (+)-retronecine (4) and (+)-integerrinecic acid (methylthio)methyl ether (6).
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