Journal of Medicinal Chemistry p. 769 - 773 (1978)
Update date:2022-07-30
Topics:
Tucker
Coope
The synthesis is described of a series of derivatives of 1-(aryloxy)-3-(arylthioalkylamino)propan-2-ols and 1-(alkylthioamino)- and 1-(aralkylamino)-3-(aryloxy)propan-2-ols. These compounds were investigated for their β-adrenoreceptor blocking properties and their selectivity of action for the cardiac β1 receptor. The structure-activity relationships are discussed with particular reference to the effects of the sulfur, sulfoxide, and sulfone groups on β-adrenoreceptor blocking potency and selectivity.
View MoreHaitong Chemical Industrial Co.,Ltd.
website:https://www.haitonglongwin.com/
Contact:+86-022-66221018
Address:18-701, No.99, The 4th Street, TEDA,
Hangzhou Bayee Chemical Co.,Ltd.
Contact:+86-571-86990109
Address:No.380, Jiangnan Auenue, Binjiang District, Hangzhou, China
Onlychem (Jinan)Biotech Co.,Ltd
Contact:86-531-83175885
Address:No. 44, Honglou South Road, Jinan,China
JIN TAN CHENG'EN CHEMICAL CO.,LTD.
Contact:86-519-82116250
Address:NO.102，village Dongfang，conomic development zone
Dalian RSD International Trade Co.,Ltd.(expird)
Contact:86-22-60875058 58610575
Address:Wantong International Areas, Hongqiao District, Tianjin, China.China
Doi:10.1016/0040-4020(78)80035-0
(1978)Doi:10.1016/S0040-4039(02)02435-8
(2002)Doi:10.1021/jo01028a012
(1964)Doi:10.1021/jo030070z
(2004)Doi:10.1021/jo01351a052
(1961)Doi:10.1016/S0040-4039(01)85417-4
(1978)
