Chemistry of Natural Compounds p. 176 - 178 (1981)
Update date:2022-08-04
Topics:
Mikhano, S. D.
Kulachkina, N. S.
Filippova, T. M.
Suchkova, I. G.
Berezovskii, V. M.
(+-)-Biotin has been synthesized from a mixture of cis- and allo-trisubstituted dehydrothiophanes by a scheme providing for the easy elimination of the accompanying allo-substituted thiophane in the form of an intermediate and not as the final isomeric allo-biotin.The imidazoline ring of biotin is formed from a dialkoxycarbonyldiaminothiophane under the conditions of partial hydrolysis of one of the protective groups with the elimination of phosgene from the scheme of synthesis.
View MoreHenan Sinotech Import&Export Corporation
website:http://www.hasinotech.com
Contact:86-371-86181678
Address:No. 260, Dongming Road,Jinshui District
Shijiazhuang Sdyano Fine Chemical Co., Ltd
Contact:+86-311-89830448
Address:NO.48 Ta Nan Road,Yuhua District,Shijiazhuang,Hebei,China
shanghai hekang chemical co.ltd
Contact:021-54173790
Address:328 WuHe Road, Building #A, 2nd Floor, Minhang, Shanghai 201109, China
Ji'nan Orgachem Pharmaceutical Co.,Ltd
Contact:+86-531-82687810
Address:Jinan
Shenyang Mole pharmaceutical Technology Development Co.,Ltd
Contact:+86-24-31204918/13889278616
Address:No.44, wanliutang road, shenhe District of Shenyang
Doi:10.1016/S0020-1693(03)00475-4
(2003)Doi:10.1002/asia.201100913
(2012)Doi:10.1002/ejoc.201101670
(2012)Doi:10.1016/S0040-4020(01)82331-0
(1991)Doi:10.1016/j.apcata.2013.11.002
(2014)Doi:10.1021/ma300090a
(2012)
