Synthesis of spiro[isobenzofuran-1(3H),4'-piperidines] as potential central nervous system agents. 4. Central nervous system depressants.

DOI: 10.1021/jm00209a012

Source and publish data:

Journal of Medicinal Chemistry p. 1149 - 1154 (1978)

Update date:2022-08-05

Topics:: Authors:

Allen,R.C. et al.

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Article abstract of DOI:10.1021/jm00209a012

The synthesis of 1''-[3-(4-fluorobenzyoyl)propyl]-3-phenylspiro[isobenzofuran-1(3H),4''-piperidine] (2a) and eight halo and methoxy analogues is described. The compounds were generally more potent per os than chlorpromazine in the Sidman avoidance paradig

Full text of DOI:10.1021/jm00209a012

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Article Doi

Synthesis of spiro[isobenzofuran-1(3H),4'-piperidines] as potential central nervous system agents. 4. Central nervous system depressants.

DOI: 10.1021/jm00209a012

Source and publish data:

Authors:

Article abstract of DOI:10.1021/jm00209a012

Full text of DOI:10.1021/jm00209a012

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