
Journal of Enzyme Inhibition and Medicinal Chemistry p. 40 - 51 (2016)
Update date:2022-08-05
Topics: Synthesis Nuclear magnetic resonance (NMR) spectroscopy High-performance liquid chromatography (HPLC) X-ray crystallography In Vitro Assays Structural Analysis
Ciccone, Lidia
Nencetti, Susanna
Rossello, Armando
Stura, Enrico Adriano
Orlandini, Elisabetta
Transthyretin (TTR), a β-sheet-rich tetrameric protein, in equilibrium with an unstable amyloidogenic monomeric form is responsible for extracellular deposition of amyloid fibrils, is associated with the onset of neurodegenerative diseases, such as senile
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