The synthesized compounds are tested in in vitro experiments using cultured cells. Cell-based assays can measure the ability of these compounds to inhibit the production of TNF-α or modulate the inflammatory response.
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3-[2-(6-chloropyridazin-3-ylamino)phenylamino]-1H-pyrazol-5(4H)-one
diazomethane
3-(1H-imidazol-1-yl)-1-phenylpropyl benzoate
Benzamide, N-(2-hydroxy-3-phenoxypropyl)-4-nitro-
3-Heptanone, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
2-(6-chloropyridin-2-yl)-4,5,6,7-tetrahydro-1,2-benzoisothiazolium perchlorate
2-amino-4-ethoxy-5-methoxybenzonitrile
(S)-2-TERT-BUTOXYCARBONYLAMINO-3-NAPHTHALEN-2-YL-PROPIONIC ACID METHYL ESTER
methyl 1-(4-chlorobenzyl)-1H-pyrrole-2-carboxylate
4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-
Ethanethioic acid, S-[2-[[(2R)-2-(acetylamino)-1-oxo-3-[(triphenylmethyl)thio]propyl]amino] ethyl] ester
5-(furan-2-yl)-8-phenyl-10-(trifluoromethyl)-2,3-dihydroimidazo[1,2-c]quinazoline-7-carboxamide
2-(2-fluorobiphenyl-4-yl)-6-phenylimidazo[2,1-b][1,3,4]thiadiazole
4-isoxazolecarboxamide, 5-amino-3-(3-chlorophenyl)-
(2S,3R,4S,5S,6R)-2-[(2R,3R,4R,5S)-4,5-Dihydroxy-2-hydroxymethyl-1-(4-methyl-benzyl)-piperidin-3-yloxy]-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
5-[5-(tert-butyl-dimethyl-silanyloxy)-pentane-1-sulfonyl]-1-phenyl-1H-tetrazole
(+)-3-PPP hydrobromide
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-N-(4-trifluoromethyl-pyridin-2-yl)benzamide
1-(4-fluorophenyl)-2-[(1-methyl-1H-tetraazol-5-yl)sulfanyl]ethanone
2-(carboxymethyl)-5-{[(3-nitrophenyl)carbonyl]amino}benzoic acid
2,6-dinitrothymol
2-(N-isobutylamino)-3-(4-methoxyphenyl)propan-1-ol
diethyl 2-((2-hydroxyethyl)(2-(trityloxy)ethyl)amino)ethylphosphonate
Silica gel
4-{4-[2-benzoyl-5-methoxyphenoxy]pyrimidin-2-ylamino}benzonitrile
EDTA
Picogreen
6-methyl-N-phenyl-4-thien-2-yl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
7-(N-(2-methoxyphenylamino)methyl)-(20S)-camptothecin
3-[(2R,3S,5R)-5-(6-chloro-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl]-1-phenylpropan-1-one
1,3-dihydro-3,3-dimethyl-1-phenylisobenzofuran-1-ol
PF-04457845
Methanone, (3,4-dichlorophenyl)phenyl-, oxime
α-methyl-δ-valerolactone
4-(2,4-Dimethoxy-phenyl)-2-(4-methoxy-phenyl)-4,5-dihydro-3H-pyrrole-3-carboxylic acid ethyl ester
tert-butyl 3-carbamoyl-2-[3-(4-chlorophenyl)ureido]-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
7-{4-[Bis-(2-chloro-ethyl)-amino]-phenyl}-heptan-1-ol
5-[[4-(2-oxo-2-phenylethoxy)phenyl]methyl]-2,4-thiazolidinedione
Benzoylcholine Chloride
N-(6-acetyl-3-methoxy-2-methylphenyl)-4-cyclopropylthiazole-2-carboxamide
Benzoic acid, 4-(acetylamino)-5-chloro-2-methoxy-3-nitro-, methyl ester
ethyl 2-[(2,4-dichloro-5-fluoro-3-nitrophenyl)carbonyl]-3-(dimethylamino)prop-2-enoate
1-methyl-4-piperidyl diphenylglycolate
2,4-dibromo-1-(4-bromobutoxy)Benzene
1-Pentanone, 2-bromo-4-methyl-1-(4-methylphenyl)-
C31H42N8O9(2-)*Ca(2+)
2-(3,4-dimethoxyphenyl)-1-(5-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethan-1-one
Ethanethioic acid, S-[[3,5-bis(trifluoromethyl)phenyl]methyl] ester
(E)-N-(3-fluoro-4-(methylsulfonamido)benzyl)-3-(4-iodophenyl)acrylamide
