Tetrahedron Letters p. 517 - 520 (1988)
Update date:2022-08-04
Topics:
Ward, Dale E.
Rhee, Chung K.
Zoghaib, Wajdi M.
Ketones can be reduced in the presence of conjugated enones by sodium borohydride in 50percent methanol in dichloromethane at -78 deg C.The selectivity is generally excellent.In favorable cases the reaction can be carried out at room temperature in dichloromethane with acetic acid as catalyst.
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