Unnatural nucleosides and nucleotides. III. Preparation of 2-14C and 4-14C labelled 5-alkyluracils and 5-alkyl-2'-deoxyuridines

DOI: 10.1002/jlcr.2580140509

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 713 - 726 (1978)

Update date:2022-08-02

Topics:

Authors:

Szabolcs

Kruppa Kruppa

Sagi Sagi

Otvos Otvos

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jlcr.2580140509

2-¹⁴C Labelled 5-alkyluracils were prepared by condensation of the diethylacetals of α-formyl-carbonic acid esters with ¹⁴C-thiourea. Compounds labelled at 4-C were synthesized by condensation of the labelled carboxylic acid derivatives with thiourea. β-Anomers of 5-alkyl-2'-deoxyuridines were obtained in a fairly good radiochemical yield. Alkyl substituents ranged from methyl to tetradecyl, isopropyl and tert-butyl.

Full text of DOI:10.1002/jlcr.2580140509

Products guided by the article

Product name:O^3',O^5'-bis-(4-chloro-benzoyl)-5-propyl-2'-deoxy-[2-¹⁴C]uridine

Cas No:69264-25-1

R&D Labs maybe for 69264-25-1

Sichuan Sangao Biochemical Co., Ltd

Contact:+86-28-84874233

Address:19F, Bldg.2, Shudu Center, Tianfu 2nd St., Hi-tech zone, Chengdu 610041, Sichuan Province, China.
Pale Palm Imex

Contact:+36(21)2523420

Address:Head office: 1102 Budapest, SZENT LASZLO TER 24/B. 1/1., HUNGARY / CHINA
Quzhou Aokai Chemical Co., Ltd.

Contact:86-570-3032832

Address:NO.16 , Laodong Road,Quzhou City, Zhejiang Province,China
LIAOYANG WANRONG CHEMICALS COMPANY LIMITED

Contact:86-419-2390789

Address:XINLI VILLAGE , DONG NINGWEI COUNTY,TAIZIHE DISTRICT, LIAOYANG , LIAONING
Hangzhou Gangjin Chemical Co.,Ltd.(expird)

Contact:+86-571-85109780

Address:707 Zhejiang Minhang Bldg., No.290 Zhongshan North Road, Hangzhou 310003, China

Relevant to this article

Preparation of useful building blocks, α-iodo- and bromoalkanols from cyclic ethers using the Dowex H⁺/NaX (X = I, Br) approach

Doi:10.1039/c5ra20813k
(2016)
Total Synthesis of (±)-Perophoramidine

Doi:10.1021/ja049569g
(2004)
Doi:10.1007/BF00487409
()
Doi:10.1016/S0008-6215(00)81557-8
(1971)
C₁₉ quassinoid model studies: Preparation of trans-perhydroindans via a vinylogous Mukaiyama aldol - Free-radical cyclization route

Doi:10.1139/v03-197
(2004)
Formation of an iron(II) carbene-thiolato complex by insertion of carbon monoxide into an Si-C bond

Doi:10.1002/anie.200352916
(2004)

Article Doi