A stereospecific synthesis of optically pure (-)-α-multistriatin

Article abstract of DOI:10.1016/S0040-4020(01)86814-9

An efficient stereo- and enantiospecific synthesis of (-) -α-multistriatin from (L)- malic acid is described. The key steps of this synthesis are the stereoselective alkylation of the hydroxylactone 5 and the acid equilibration of the esters 9 and 10.