Use of the butaclamol template in a search for antipsychotic agents with lessened side effects

DOI: 10.1021/jm00190a009

Source and publish data:

Journal of Medicinal Chemistry p. 401 - 406 (1979)

Update date:2022-09-26

Topics:

Authors:

Kukla Kukla

Bloss Bloss

Brougham

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Article abstract of DOI:10.1021/jm00190a009

A number of molecular similarities between the antipsychotic agents butaclamol and clozapine were noted. Based on the premise that this was a strong indicator of a common mechanism of action (i.e., binding at the antagonist state of dopamine receptor), a

Full text of DOI:10.1021/jm00190a009

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