Journal of the Chemical Society. Perkin transactions II p. 1645 - 1648 (1983)
Update date:2022-09-26
Topics: Chiral Nucleophile Organometallic reagents Condensation Reactions Stereoselectivity
Alvarez-Ibarra, Carlos
Arjona, Odon
Perez-Ossorio, Rafael
Perez-Rubalcaba, Alfredo
Quiroga, Maria L.
Santesmases, Maria J.
Stereochemical results of the condensation reactions of a series of ketones, PhCHMeCOR (R= Me, Et, Pri, But, Ph), with various organomagnesium and organolithium derivatives in ethers as solvents are reported.Results are accounted for on the basis of competition between two transition states which may adopt either Karabatsos- or Felkin-type conformations according to the nature of R, the reagent nucleophilicity, and the polarity of solvent.Polar and steric analysis of this reaction allows highly stereoselective syntheses of diastereoisomeric α-phenylalkanols to be devised.
View MoreChengdu Aslee Biopharmaceuticals, Inc
Contact:18608018419
Address:Chengdu Aslee Biopharmaceuticals, Inc
Shanghai Haoyuan Chemexpress Co., Ltd.
website:https://www.chemexpress.com/
Contact:86-21-58950125
Address:No.3 Building, No.1999, Zhangheng Road, ZhangjiangHighTech Park, Shanghai, P.R.China,201203
Changde Yungang Biotechnology Co., Ltd
website:http://www.cdyg.com
Contact:+86-736-7391178
Address:Qiaonan Industrial Park, Changde City, Hunan Province
SHANGHAI RC CHEMICALS CO.,LTD.
website:http://www.rcc.net.cn
Contact:+86-21-50322175
Address:Rm1415 Yinqiao Masion No.58 Jinxin Road Pudong Shanghai China
Jiangsu Wanlong Chemical Co., Ltd.
website:http://www.wanlongchem.com
Contact:+86-511-86810993 0086-511-8681 0888;
Address:Quanzhou Town, Danyang City, Jiangsu
Doi:10.1021/jf60161a609
(1969)Doi:10.1002/jhet.5570410220
(2004)Doi:10.1039/jr9500000395
(1950)Doi:10.1039/c39790000121
(1979)Doi:10.1039/c9gc00289h
(2019)Doi:10.1016/j.bmcl.2004.03.108
(2004)
