Journal of Medicinal Chemistry p. 882 - 885 (1979)
Update date:2022-08-05
Topics:
Okruszek
Verkade
The synthesis of the title compound from 3'-amino-3'-deoxyadenosine in 40% yield is reported. 3'-Amino-3'-deoxyadenosine was made by an improved synthesis in 12 steps from inexpensive D-xylose in 15% overall yield. Both isomers of the title compound, separated by column chromatography, possess confirmed activity against KB tumor cell cultures.
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Doi:10.1021/ml400027y
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(1956)
