Journal of Organic Chemistry p. 1367 - 1371 (1988)
Update date:2022-08-03
Topics:
Trecourt, F.
Mallet, M.
Marsais, F.
Queguiner, G.
Directed ortho lithiation of 2-methoxypyridine (1) has been regioselectively achieved at position 3 by using methyllithium catalyzed by a small amount of diisopropylamine.This metalation methodology, called "catalyzed metalation", gave good results whereas other metalation routes failed.This allowed the convenient synthesis of various 3-substituted 2-methoxypyridines of general interest.
View MoreLiao Cheng All Win Chemicals Co.,LTD
Contact:86+0635-2991582
Address:Room 402,Unit 1,No.27 building.Zhong tong shi dai haoyuan,liaocheng city,Shan dong Province.China
Shanghai Yingrui Biopharma Co., Ltd
Contact:021-3358 8661*8003
Address:shanghai
Xuzhou Tianrun Chemical Co.,Ltd
website:http://www.tianrunchem.cn
Contact:86-516-83832636
Address:fuxing road
Contact:410-273-7300; 800-221-3953
Address:4609 Richlynn Dr., PO Box 369, Belcamp, MD, 21017-0369, USA
Evergreen Chemical Industry Ltd.
Contact:86-553-4918210
Address:6#2-602 Wanhaobailing
Doi:10.1016/j.tetlet.2017.05.009
(2017)Doi:10.1016/j.tet.2007.05.079
(2007)Doi:10.1002/ejoc.200300764
(2004)Doi:10.1080/15533174.2012.684237
(2013)Doi:10.1055/s-2002-34389
(2002)Doi:10.1246/bcsj.41.1472
(1968)
