A new nontricyclic antidepressant agent. Synthesis and activity of N-[trans-2-(dimethylamino)cyclopentyl]-N-(3,4-dichlorphenyl)propanamide and related compounds

DOI: 10.1021/jm00142a020

Source and publish data:

Journal of Medicinal Chemistry p. 1230 - 1236 (1981)

Update date:2022-07-30

Topics: Synthesis Activity Related compounds Dimethylamino Cyclopentyl Propanamide

Authors:

Szmuszkovicz

Von Voigtlander

Kane Kane

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Article abstract of DOI:10.1021/jm00142a020

A series of new nontricyclic antidepressant compounds was synthesized. A representative of this class is shown. Five structural parameters were investigated: ring size, cis/trans stereochemistry, amide substitution, aromatic substitution, and amine substi

Full text of DOI:10.1021/jm00142a020

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