Journal of Medicinal Chemistry p. 1230 - 1236 (1981)
Update date:2022-07-30
Topics: Synthesis Activity Related compounds N-[trans-2-(dimethylamino)cyclopentyl]-N-(3,4-dichlorphenyl)propanamide Nontricyclic antidepressant Dimethylamino Cyclopentyl 3,4-dichlorphenyl Propanamide
Szmuszkovicz
Von Voigtlander
Kane
A series of new nontricyclic antidepressant compounds was synthesized. A representative of this class is shown. Five structural parameters were investigated: ring size, cis/trans stereochemistry, amide substitution, aromatic substitution, and amine substi
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