CERIUM CHLORIDE-PROMOTED NUCLEOPHILIC ADDITION OF GRIGNARD REAGENTS TO KETONES AN EFFICIENT METHOD FOR THE SYNTHESIS OF TERTIARY ALCOHOLS

Article abstract of DOI:10.1016/S0040-4039(00)94945-1

In the presence of anhydrous cerium(III) chloride, Grignard reagents react with ketones to afford addition products in high yields, even though the substrates are susceptible to abnormal reactions with Grignard reagents alone.