Journal of Organic Chemistry p. 261 - 264 (1980)
Update date:2022-08-04
Topics:
Cere, Vanda
Guenzi, Alberto
Pollicino, Salvatore
Sandri, Edda
Fava, Antonino
The concerted fragmentation method of Whitham has been applied to the configurational inversion of cis-thiacyclooct-4-ene (1) to give (35percent overall yield) trans-thiacyclooct-4-ene (2) of >98 percent configurational purity.The required protection of the S atom has been afforded by methylation, while deprotection was achieved by homogeneous LiAlH4 reduction in THF.Some peculiar NMR properties of the 1-methyl and 1-oxide derivatives of trans-thiacyclooctene are reported.
View MoreContact:0086-29-88315623
Address:S711, Innovation Bldg No.25 Gaoxin 1st Rd, Xian P.R of China 710075
website:http://www.truewingroup.com
Contact:86-311-66699812
Address:NO.600 ZHONGSHAN EAST ROAD SHIJIAZHUANG
Taizhou Huading Chemical Co.,Ltd(expird)
Contact:+86-576-88583898
Address:Economic&Technology development zone,Taizhou City,Zhejiang Province,China
Shijiazhuang City Xiehe Pharmaceutical Co., Ltd
Contact:+86-311-80817929
Address:Shangzhuang,Shijiazhuang,China
Zhejiang Haizhou Pharmaceutical Co., Ltd.
website:https://www.haizhoupharma.com/
Contact:+86-576-88221016
Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Doi:10.1021/ol702279w
(2007)Doi:10.1021/ja01176a046
(1949)Doi:10.1021/ja00518a035
(1977)Doi:10.1002/anie.201402229
(2014)Doi:10.1016/0008-6215(79)80008-7
(1979)Doi:10.1016/0040-4039(88)85139-6
(1988)
