Journal of Organic Chemistry p. 261 - 264 (1980)
Update date:2022-08-04
Topics:
Cere, Vanda
Guenzi, Alberto
Pollicino, Salvatore
Sandri, Edda
Fava, Antonino
The concerted fragmentation method of Whitham has been applied to the configurational inversion of cis-thiacyclooct-4-ene (1) to give (35percent overall yield) trans-thiacyclooct-4-ene (2) of >98 percent configurational purity.The required protection of the S atom has been afforded by methylation, while deprotection was achieved by homogeneous LiAlH4 reduction in THF.Some peculiar NMR properties of the 1-methyl and 1-oxide derivatives of trans-thiacyclooctene are reported.
View MoreNaturalin Bio-Resource Co., Ltd
website:http://www.naturalin.com
Contact:+86-0731-84430651
Address:B1-402, Lu-Valley Enterprise Square.No.27 Wenxuan Road. Lu-Valley Hi-Tech District.
Contact:86-15588110016
Address:LINYI CITY,SHANDONG PROVINCE,CHINA
Hubei Sibo Technology Co.,Ltd.
Contact:0715-6597222
Address:Pan Jia Wan fan Lake Chemical Industrial Park ,Xianning City, Hubei, China
Kunming Biohome Technology Co. Ltd.
website:http://www.biohometech.com/
Contact:86-871-67428869
Address:kunming
Quzhou Hopemax Chemical Technology Co.Ltd
Contact:86-570-3036007
Address:Room 801,Building 2,Wealth Center,No.51,Xujiang Road,Quzhou,China.
Doi:10.1021/ol702279w
(2007)Doi:10.1021/ja01176a046
(1949)Doi:10.1021/ja00518a035
(1977)Doi:10.1002/anie.201402229
(2014)Doi:10.1016/0008-6215(79)80008-7
(1979)Doi:10.1016/0040-4039(88)85139-6
(1988)
