7-(Triflluoromethyl)-4-aminoquinoline Hypotensives: Novel Peripheral Sympatholytics

DOI: 10.1021/jm00151a021

Source and publish data:

Journal of Medicinal Chemistry p. 133 - 137 (1986)

Update date:2022-08-05

Topics:

Authors:

McCall, John M.

TenBrink, R. E.

Kamdar, Bharat V.

Skaletzky, Louis L.

Perricone, Salvatore C.

et al. et al.

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Article abstract of DOI:10.1021/jm00151a021

A family of 7-(trifluoromethyl)-4-aminoquinolines that are hypotensive agents and that act by a novel sympatholytic mechanism is described.Structure-activity relationships in this series have been elucidated.Some of the more potent hypotensives were evalu

Full text of DOI:10.1021/jm00151a021

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