acetic Acids. A New Diuretic Series

DOI: 10.1021/jm00343a008

Source and publish data:

Journal of Medicinal Chemistry p. 36 - 44 (1982)

Update date:2022-08-05

Topics:

Authors:

Shutske, Gregory M.

Setescak, Linda L.

Allen, Richard C.

Davis, Larry

Effland, Richard C.

et al. et al.

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Article abstract of DOI:10.1021/jm00343a008

A series of <(3-aryl-1,2-benzisoxazol-6-yl)oxy>acetic acids was synthesized and tested for diuretic activity in saline-loaded mice and in conscious, water-loaded dogs.The structural requirements for good diuretic activity in both mice and dogs were found

Full text of DOI:10.1021/jm00343a008

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