Peptide Sweeteners. 3. Effect of Modifying the Peptide Bond on the Sweet Taste of L-Aspartyl-L-phenylalanine Methyl Ester and Its Analogues

DOI: 10.1021/jm00178a012

Source and publish data:

Journal of Medicinal Chemistry p. 413 - 420 (1980)

Update date:2022-08-05

Topics:

Authors:

MacDonald, Scott A.

Willson, C. Grant

Chorev, Michael

Vernacchia, Fred S.

Goodman, Murray

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Article abstract of DOI:10.1021/jm00178a012

A series of analogues designed to assess the importance of the amide bond in the dipeptide sweetener L-aspartyl-L-phenylalanine methyl ester has been synthesized and tested.The peptide bond was methylated, replaced by an ester bond, or reversed.All of the

Full text of DOI:10.1021/jm00178a012

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Product name:N-(benzyloxycarbonyl)-β-benzyl-L-aspartyl-N-methyl-L-phenylalanine methyl ester

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