Journal of Medicinal Chemistry p. 413 - 420 (1980)
Update date:2022-08-05
Topics:
MacDonald, Scott A.
Willson, C. Grant
Chorev, Michael
Vernacchia, Fred S.
Goodman, Murray
A series of analogues designed to assess the importance of the amide bond in the dipeptide sweetener L-aspartyl-L-phenylalanine methyl ester has been synthesized and tested.The peptide bond was methylated, replaced by an ester bond, or reversed.All of the
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