Studies on diazepines. VII Syntheses of novel 1H-1,2-diazepines condensed with aromatic heterocyclic rings

Article abstract of DOI:10.1248/cpb.27.2183

Irradiation of the fused pyridium ylides or their dimers prepared from 1,5- and 1,8-naphthyridine, thieno [2,3-b]- and thieno [3,2-b]-pyridine, and furo [2,3-b]-pyridine by N-amination with O-mesitylentsulfonylhydroxylamine followed by treatment with base, resulted in the formation of the corresponding fused 1H-1,2-diazepines which are previously unknown bicyclic ring systems. However, a similar synthetic route from the pyrrolopyridines failed to yield pyrrolodiazepines.