Synthesis of 3,4-Dihydro-4-(2-hydroxyphenyl)pyridopyrimidin-2(1H)-ones by a Novel Rearrangement of a 5H-Benzopyranopyridine Derivative

DOI: 10.1021/jo01298a032

Source and publish data:

Journal of Organic Chemistry p. 1918 - 1920 (1980)

Update date:2022-08-05

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Authors:

Bristol, James A.

Lovey, Raymond G.

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Article abstract of DOI:10.1021/jo01298a032

The benzopyrano<2,3-b>pyridine 4 undergoes a facile base-induced ring rearrangement in the form of its monoanion derivatives 5 or 7 to afford the pyrido<2,3-d>pyrimidin-2(1H)-ones 8a and 8b, respectively.Deuteration experiments confirm the formation of th

Full text of DOI:10.1021/jo01298a032

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