Studies on the Syntheses of Heterocyclic Compounds. 800. A Formal Total Synthesis of (+/-)-Thienamycin and (+/-)-Decysteaminylthienamycin Derivative

DOI: 10.1021/ja00526a048

Source and publish data:

Journal of the American Chemical Society p. 2060 - 2065 (1980)

Update date:2022-08-05

Topics:

Authors:

Kametani, Tetsuji

Huang, Shyh-Pyng

Yokohama, Shuichi

Suzuki, Yukio

Ihara, Masataka

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00526a048

The synthesis of a key intermediate for the preparation of (+/-)-thienamycin (1) and its derivatives has been developed.By 1,3-dipolar cycloaddition, the nitrile oxide derived from 3-nitropropanal dimethyl acetal (3) was added to methyl crotonate to give

Full text of DOI:10.1021/ja00526a048

Products guided by the article

Product name:{(2R,3S)-2-(2,2-Dimethoxy-ethyl)-3-[(S)-1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-hydroxy-acetic acid 2-nitro-benzyl ester

Cas No:72679-66-4

R&D Labs maybe for 72679-66-4

Beyond Pharmaceutical Co., Ltd

Contact:+86-571-8195-3185

Address:No. 13-1, Liansheng Road, Yuhang District
Tengzhou Runlong Fragrance Co., Ltd.

website:http://www.tzrunlong.com/

Contact:--

Address:No. 78, Fushan Road, Biomedical Industrial Park, Dawu Town, Tengzhou, Shandong, 277514 China
Taizhou KEDE Chemical.Co.,Ltd.

Contact:86-576-84613060

Address:Jiangkou Chemical Zoon
WD Silicone Co., Ltd

Contact:+86-27-87204219, +86-27-87215023

Address:2402, HuiGu Space-time Building, 8 Forest Road, East Lake Hi-Tech Development Zone
Taizhou Crene Biotechnology co.ltd

Contact:86-576-88813233 88205808

Address:Economic Developed Zone of Taizhou Zhejiang China

Relevant to this article

Mechanism of Selective C-H Hydroxylation Mediated by Manganese Aminopyridine Enzyme Models

Doi:10.1021/cs5013206
(2015)
Doi:10.1007/BF00902810
(1951)
Synthesis of enantiomerically pure (R,R)- and (S,S)-1,2-Bis(pentafluorophenyl)ethane-1,2-diamine and evaluation of the pK _a value by ab initio calculations

Doi:10.1246/bcsj.77.1001
(2004)
Unusual visible-light photolytic cleavage of tertiary amides during the synthesis of cyclolignans related to podophyllotoxin

Doi:10.1016/j.tet.2017.09.021
(2017)
Solid phase synthesis of acylglycine human metabolites

Doi:10.1016/j.bmcl.2009.09.118
(2009)
Doi:10.1007/BF00471904
()

Article Doi