Studies on the Syntheses of Heterocyclic Compounds. 800. A Formal Total Synthesis of (+/-)-Thienamycin and (+/-)-Decysteaminylthienamycin Derivative

DOI: 10.1021/ja00526a048

Source and publish data:

Journal of the American Chemical Society p. 2060 - 2065 (1980)

Update date:2022-08-05

Topics:

Authors:

Kametani, Tetsuji

Huang, Shyh-Pyng

Yokohama, Shuichi

Suzuki, Yukio

Ihara, Masataka

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00526a048

The synthesis of a key intermediate for the preparation of (+/-)-thienamycin (1) and its derivatives has been developed.By 1,3-dipolar cycloaddition, the nitrile oxide derived from 3-nitropropanal dimethyl acetal (3) was added to methyl crotonate to give

Full text of DOI:10.1021/ja00526a048

Products guided by the article

Product name:{(2R,3S)-2-(2,2-Dimethoxy-ethyl)-3-[(S)-1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-hydroxy-acetic acid 2-nitro-benzyl ester

Cas No:72679-66-4

R&D Labs maybe for 72679-66-4

PharmaResources(Kaiyuan)CO,.Ltd

Contact:+86-21-50720028

Address:No.3, Beihuan Road, Economic Development District, Kaiyuan City, Tieling City, Liaoning Province, China 112300
Suzhou BEC Fine Chemicals Co., Ltd.

website:http://www.bek.com.cn

Contact:0512-68095917　 18913193865

Address:6, Jin Shan Road, Suzhou New District, 215011 China Suzhou Nations Pharmaceutical Innovation Center Inside
HANGZHOU ICH BIOFARM CO.,LTD

Contact:+86-571-28186845

Address:Room 1224,Eastcom Mansion,398 Wensan Road,Hangzhou,310013 China
Tianjin Emulsion Science&Technology Development Co.,Ltd

Contact:13901380442

Address:Vake Garden New Town New Yi Bai Road Beichen District Tianjin,China
Changzhou Hopschain Chemical Co.,Ltd

website:http://www.hopschem.cn/products.html

Contact:86-519-85528066

Address:Room 710, Unit A, Xingbei Development Mansion, Tongjiang Road, Changzhou City,213000, China

Relevant to this article

Mechanism of Selective C-H Hydroxylation Mediated by Manganese Aminopyridine Enzyme Models

Doi:10.1021/cs5013206
(2015)
Doi:10.1007/BF00902810
(1951)
Synthesis of enantiomerically pure (R,R)- and (S,S)-1,2-Bis(pentafluorophenyl)ethane-1,2-diamine and evaluation of the pK _a value by ab initio calculations

Doi:10.1246/bcsj.77.1001
(2004)
Unusual visible-light photolytic cleavage of tertiary amides during the synthesis of cyclolignans related to podophyllotoxin

Doi:10.1016/j.tet.2017.09.021
(2017)
Solid phase synthesis of acylglycine human metabolites

Doi:10.1016/j.bmcl.2009.09.118
(2009)
Doi:10.1007/BF00471904
()

Article Doi