Fluorinated Retinoic Acids and Their Analogues. 2. Synthesis and Biological Activity of Aromatic 4-Fluoro Analogues

DOI: 10.1021/jm00133a020

Source and publish data:

Journal of Medicinal Chemistry p. 101 - 104 (1981)

Update date:2022-07-29

Topics:

Authors:

Chan, Ka-Kong

Specian, Anthony C.

Pawson, Beverly A.

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Article abstract of DOI:10.1021/jm00133a020

Ethyl (E,Z,E,E)-3,7-dimethyl-4-fluoro-9-(4-methoxy-2,3,6-trimethylphenyl)nonatetraenoate (10a) has been found to cause a marked regression of chemically induced skin papillomas in mice.A new synthesis of this compound was achieved by condensation of 4-flu

Full text of DOI:10.1021/jm00133a020

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