Journal of Medicinal Chemistry p. 690 - 692 (1980)
Update date:2022-07-30
Topics:
Watthey, Jeffrey W. H.
Desai, Mahesh
Rutledge, Richard
Dotson, Ronald
The synthesis of an analogue of amiloride in which the acylguanidine moiety has been replaced by a 1,2,4-oxadiazol-3-amine unit is described.This substance (3, CGS 4270) exhibited a diuretic profile similar to that of amiloride when evaluated in the rat a
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Doi:10.1007/BF00951887
(1980)Doi:10.1007/BF01172289
(1991)Doi:10.1016/S0957-4166(00)00027-6
(2000)Doi:10.1007/s11172-007-0118-9
(2007)Doi:10.1055/s-1980-28949
(1980)Doi:10.1016/j.tetlet.2013.03.123
(2013)