
Chemical and Pharmaceutical Bulletin p. 3518 - 3524 (1984)
Update date:2022-08-05
Topics:
Ohshima
Takatsuto
Ikekawa
DeLuca
1α-Fluorovitamin D3 has been synthesized from 6β-acetoxy-5α-cholest-1-en-3-one (2) via 1α-fluorocholesterol (11). The key reaction was the trans diaxial ring opening of the 1β,2β-epoxide 5 with potassium hydrogen difluoride in ethyleneglycol by
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Doi:10.1016/S0968-0896(00)00026-2
(2000)Doi:10.1016/S0040-4020(01)98879-9
(1981)Doi:10.1007/BF02401714
(1980)Doi:10.1021/acs.joc.0c01170
(2020)Doi:10.1021/jm050597z
(2005)Doi:10.1002/chem.202100939
(2021)