The synthesis of 11a-carbathromboxane A2

DOI: 10.1016/S0040-4039(00)71428-6

Source and publish data:

Tetrahedron Letters p. 445 - 448 (1980)

Update date:2022-08-03

Topics:

Authors:

Maxey Maxey

Bundy Bundy

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Article abstract of DOI:10.1016/S0040-4039(00)71428-6

The chemically stable thromboxane analog 11a-carbathromboxane A₂ (1) was synthesized from PGA₂ in 12 steps. 11a-Carba-TXA₂ inhibits PGH₂-induced aggregation of human platelets.

Full text of DOI:10.1016/S0040-4039(00)71428-6

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