ON THE CHEMISTRY OF FLAVIN-DEPENDENT OXYGEN ACTIVATION III. SYNTHESIS OF 1.10A-DIHYDROFLAVIN AND ITS 10.10a-RING OPENED DERIVATIVE AS MODEL CHROMOPHORES FOR ENZYME-BOUND INTERMEDIATES

Article abstract of DOI:10.1016/S0040-4039(00)71460-2

Model chromophores of 1.10-dihydroflavin and its 10.10a-ring opened derivative have been isolated.By comparison with enzymatic intermediates, reaction mechanisms of flavin-dependent oxygenase and luciferase are discussed in terms of chemical structure.