
Journal of Medicinal Chemistry p. 1232 - 1235 (1980)
Update date:2022-08-03
Topics:
Hsu, Fu-Lian
Hamada, Akihiko
Booher, Mark E.
Fuder, H.
Patil, P. N.
Miller, Duane D.
The synthesis and α-adrenergic blocking activity of a series of optically active 2,4-disubstituted imidazolines are presented.The substituted analogues of naphazoline, tolazoline, and clonidine possess moderate α-adrenergic blocking activity with -logK
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Doi:10.1002/chem.201203444
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(1980)Doi:10.1016/j.molstruc.2018.10.080
(2019)