Improved synthesis of tadalafil using dimethyl carbonate and ionic liquids

DOI: 10.1039/c3ra45982a

Source and publish data:

RSC Advances p. 1204 - 1211 (2014)

Update date:2022-08-05

Topics:

Authors:

Earle, Martyn J.

Noe, Marco

Perosa, Alvise

Seddon, Kenneth R.

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Article abstract of DOI:10.1039/c3ra45982a

An improved synthesis of tadalafil, a drug for the treatment of male erectile dysfunction, involves the use of safer solvents and reagents as well as a reduced number of steps.

Full text of DOI:10.1039/c3ra45982a

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