Journal of Medicinal Chemistry p. 5005 - 5014 (2003)
Update date:2022-08-03
Topics:
Senten, Kristel
Van der Veken, Pieter
De Meester, Ingrid
Lambeir, Anne-Marie
Scharpé, Simon
Haemers, Achiel
Augustyns, Koen
In this paper we report the systematic search for new, potent, and selective DPP II inhibitors. A study of the structure-activity relationship was conducted starting from aminoacyl pyrrolidides as lead compounds. Rational exploration of the P1
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