DNA Intercalating Compounds as Potential Antitumor Agents. 1. Preparation and Properties of 7H-Pyridocarbazoles

DOI: 10.1021/jm00186a009

Source and publish data:

Journal of Medicinal Chemistry p. 1330 - 1335 (1980)

Update date:2022-08-03

Topics:

Authors:

Pelaprat, Didier

Oberlin, Robert

Le Guen, Irene

Roques, Bernard P.

Pecq, Jean-Bernard Le

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00186a009

The DNA Intercalating compounds derived from 6H-pyridocarbazole (ellipticines, olivacines) elicit high antitumor properties.In order to get information about the mechanism of action of these agents it is necessary to study structurally related analogues.F

Full text of DOI:10.1021/jm00186a009

Products guided by the article

Product name:10-methoxy-7-methyl-7H-pyrido[3,2-c]carbazole

Cas No:75413-44-4

R&D Labs maybe for 75413-44-4

xuri chemicals co., ltd

Contact:86-516-66656369

Address:The west road of Huaihai, Xuzhou, China
Tianjin Dongchang Fine Chemical Industry Co., Ltd.

Contact:+86-22-29894595

Address:Economic Developing Zone, Ji County, Tianjin, China
Xian Lyphar Biotech Co., Ltd.

Contact:0086-29-89196322

Address:North of the Fifth Keji Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China
Daqing E-shine Chemical Co.,LTD

Contact:0086-024-31285112

Address:Hongweiyuan area, Ranghulu district
Zibo Xiaoguang Chemical Material Co., Ltd

Contact:15954099116

Address:Boshan Development Zone

Relevant to this article

Oxidative heck vinylation for the synthesis of complex dienes and polyenes

Doi:10.1021/ja402891m
(2013)
Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design

Doi:10.1021/acs.jmedchem.7b01884
(2018)
Discovery of BIIB068: A Selective, Potent, Reversible Bruton's Tyrosine Kinase Inhibitor as an Orally Efficacious Agent for Autoimmune Diseases

Doi:10.1021/acs.jmedchem.0c00702
(2020)
Metal-free oxidative ipso-carboacylation of alkynes: Synthesis of 3-acylspiro[4,5]trienones from N-arylpropiolamides and aldehydes

Doi:10.1021/jo5005982
(2014)
Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases

Doi:10.1016/j.bmcl.2014.02.075
(2014)
Tunable Phosphine-Triggered Cascade Reactions of MBH Derivatives and 3-Acyl-2H-chromen-2-ones: Highly Selective Synthesis of Diverse Chromenones

Doi:10.1002/ejoc.201301358
(2014)

Article Doi