Synthesis and some pharmacological properties of [8-L-tryptophan]oxytocin.

DOI: 10.1021/jm00185a025

Source and publish data:

Journal of medicinal chemistry p. 1259 - 1261 (1980)

Update date:2022-08-04

Topics:

Authors:

Bodanszky

Tolle Tolle

Seto Seto

Sawyer Sawyer

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Article abstract of DOI:10.1021/jm00185a025

Condensation of (tert-butyloxycarbonyl)tocinoic acid with L-prolyl-L-tryptophylglycinamide produced the Boc derivative of a nonapeptide (disulfide) which on deprotection afforded [8-L-tryptophan]oxytocin. In assays on the rat uterus in vitro and in vivo t

Full text of DOI:10.1021/jm00185a025

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