Development of active center-directed inhibitors against plasmin

DOI: 10.1248/cpb.39.2340

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2340 - 2346 (1991)

Update date:2022-08-05

Topics:

Authors:

Teno Teno

Wanaka Wanaka

Okada Okada

Tsuda Tsuda

Okamoto Okamoto

Hijikata-Okunomiya

Naito Naito

Okamoto Okamoto

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Article abstract of DOI:10.1248/cpb.39.2340

Active center-directed inhibitors of plasmin were designed based on the structure of specific substrates of plasmin and then synthesized. Their effects on plasmin were examined and the structure-inhibitory activity relationship was studied. N(α)-trans-4-A

Full text of DOI:10.1248/cpb.39.2340

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