SYNTHESIS OF O-α-L-FUCOPYRANOSYL-(1-->3)-O-β-D-GALACTOPYRANOSYL-(1-->4)-D-GLUCOSE (3'-O-α-L-FUCOPYRANOSYLLACTOSE), AND AN IMPROVED ROUTE TO ITS β-(1"-->3')-LINKED ISOMER

Article abstract of DOI:10.1016/S0008-6215(00)85429-4

Isopropylidenation of lactose with 2,2-dimethoxypropane in N,N-dimethylformamide at 80-85 degC gave a 1:2 mixture of the kinetically favored 4',6'-acetal 1 and the thermodynamically more-stable 3',4'-acetal 2, which were separated by chromatography.The 1,