Bioorganic and Medicinal Chemistry Letters p. 2469 - 2472 (1999)
Update date:2022-07-29
Topics:
Ryu, Chung-Kyu
Jung, Sung-Hee
Lee, Joung-Ah
Kim, Hwa-Jung
Lee, Soo-Hwan
Chung, Jin-Ho
6-Arylamino-5,8-quinolinediones 3 and 7-arylamino-5,8-isoquinolinediones 4 were synthesized as inhibitors of endothelium-dependent vasorelaxation. The quinones inhibited the vasorelaxation of rat aorta with the endothelium. Among them, the quinones 3a, 3b
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