Addition of Aromatic Thiols to Conjugated Cycloalkenones, Catalyzed by Chiral β-Hydroxy Amines. A Mechanistic Study on Homogeneous Catalytic Asymmetric Synthesis

DOI: 10.1021/ja00392a029

Source and publish data:

Journal of the American Chemical Society p. 417 - 430 (1981)

Update date:2022-07-30

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Authors:

Hiemstra, Henk

Wynberg, Hans

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Article abstract of DOI:10.1021/ja00392a029

Reactions between aromatic thiols and conjugated cycloalkenones afford optically active 3-arylthiocycloalkanones, when chiral bases are used as catalysts.This paper reports a detailed investigation into the mechanism of this catalytic asymmetric synthesis

Full text of DOI:10.1021/ja00392a029

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