Tetrahedron Letters p. 1023 - 1026 (1982)
Update date:2022-08-03
Topics:
Girard, Yves
Larue, Marie
Jones, Thomas R.
Rokach, Joshua
A simple one-step preparation of the sulfones of Leukotriene C4, D4 and E4 has been developed by the direct oxidation of the parent compounds.An alternative synthesis of these sulfones has also been carried out by reduction of an acetylenic precursor.
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