Journal of the Chemical Society. Perkin transactions I p. 2755 - 2761 (1980)
Update date:2022-08-04
Topics:
Kobayashi, Yoshiro
Yamamoto, Kenjiro
Asai, Toyohira
Nakano, Masanori
Kumadaki, Itsumaro
Halogenated nucleoside derivatives were trifluoromethylated using a solution of a trifluoromethyl-copper complex, which was prepared by shaking trifluoromethyl iodide and copper powder in hexamethylphosphoric triamide and filtering off the excess of copper powder.The following trifluoromethylated nucleosides were obtained in moderate to good yields: 5-trifluoromethyl-uridine, -deoxyuridine, -cytidine, -deoxycytidine, and arabinosylcytosine; 8-trifluoromethyl-adenosine, -deoxyadenosine, and -inosine; and 6-trifluoromethylribofuranosylpurine.This procedure offers simple synthesis of many trifluoromethyl compounds.
View MoreShanggao Ruiya Fine Chemicals Co., Ltd
Contact:+86-795-2592103
Address:Xingguang Nanlu,Shanggao County Industry Park
Contact:86-21-57725962
Address:shanghai
zhenjiang runjing high purity chemical co ltd
Contact:+86-511-83361155
Address:No.8.haixi road,international chemical park
Shaanxi Lighte Optoelectronics Material Co., Ltd.
Contact:+86-29-88320728-622/619/620
Address:No.55 INDUSTRY ROAD 2,XI'AN NATIONAL CIVIL AEROSPACE INDUSTRIAL PARK.XI'AN China 710065.
Wuxi Innopal International Trade CO.,LTD
Contact:+86-510-80711901-8003
Address:Room 402,Building 5,Longze Garden,No.17,South huanjiu Road,Yixing City, Jiangsu,China
Doi:10.1002/jccs.200400024
(2004)Doi:10.1021/jo00322a016
(1981)Doi:10.1016/S0040-4039(00)92830-2
(1980)Doi:10.1007/s11164-017-2872-0
(2017)Doi:10.1016/S0040-4039(00)78738-7
(1980)Doi:10.1080/00397919208019085
(1992)
